SPRAVATO™ (Es Ketamine) nasal spray is a different kind of medication taken with an oral antidepressant for adults with treatment-resistant depression – a first in decades approved by the FDA.

Alfredo Arellano, PMHCNS-BC, PA
Certified Spravado treatment center located in El Paso Texas and serving all of El Paso, Horizon City, Sunland Park, and Fort Bliss.
Spravato is only available at certified treatment centers under the supervision of a healthcare professional.
Because of the risks for sedation, dissociation and abuse and misuse, your doctor will enroll you in Risk Evaluation and Mitigation Strategy (REMS) Program.

Most common side effects of SPRAVATO™:
- Dissociation, dizziness, nausea, sedation, spinning sensation, reduced sense of touch and sensation, anxiety, lack of energy, increased blood pressure, vomiting and feeling drunk.
- If these common side effects occur, they usually happen right after taking SPRAVATO™ and go away the same day.
- These are not all the possible side effects of SPRAVATO™ Click here to learn more
Dosing
- SPRAVATO® is taken with an oral antidepressant
- You administer SPRAVATO® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO® treatment center
- SPRAVATO® is taken twice a week for the first four weeks
- After the first four weeks, SPRAVATO® is taken once a week for a month
- After this, SPRAVATO® is usually taken either once a week or once every two weeks
Safety and Tolerability
- SPRAVATO® nasal spray was evaluated for safety in both short- and long-term clinical trials of adults diagnosed with treatment-resistant depression
- Do not take SPRAVATO® if you have a blood vessel disease (aneurysm), an abnormal connection between your blood vessels (arteriovenous malformation), a history of bleeding in the brain or are allergic to esketamine, ketamine or any of the ingredients in SPRAVATO®. Talk to your healthcare provider to learn more